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Pharmacokinetic data indicate that hepatic impairment decreases the rate of conversion of valaciclovir to aciclovir but not the extent of conversion.

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Se debe mantener una adecuada hidratación para prevenir la precipitación de aciclovir en los túbulos renales?

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This side effect may be the result of reduced vitamin K activity and/or reduced vitamin K production by bacteria in the colon.

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